Shanxian Chemical
PRODUCTS
N-Ethylbutylamine
Shanxian Chemical
|
HS Code |
926740 |
| Chemical Formula | C6H15N |
| Molar Mass | 101.19 g/mol |
| Appearance | Colorless liquid |
| Odor | Ammonia - like odor |
| Density | 0.746 g/cm³ |
| Boiling Point | 109 - 110 °C |
| Melting Point | -70 °C |
| Solubility In Water | Slightly soluble |
| Flash Point | 12 °C |
| Vapor Pressure | 5.33 kPa (25 °C) |
| Refractive Index | 1.412 (20 °C) |
As an accredited N-Ethylbutylamine factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | N - Ethylbutylamine packaged in 5 - liter containers for chemical use. |
| Storage | N - Ethylbutylamine should be stored in a cool, well - ventilated area, away from heat, sparks, and open flames due to its flammability. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents, acids, and other incompatible substances to avoid chemical reactions. Follow local safety regulations for proper storage. |
| Shipping | N - Ethylbutylamine is shipped in tightly - sealed, corrosion - resistant containers, following strict regulations for hazardous chemicals. Packaging ensures no leakage during transit to safeguard handlers and the environment. |
Competitive N-Ethylbutylamine prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365186327 or mail to info@liwei-chem.com.
We will respond to you as soon as possible.
Tel: +8615365186327
Email: info@liwei-chem.com
Historical Development
N-Ethylbutylamine is an organic compound, and its historical development is very interesting. In the past, chemical research was just beginning, and scholars devoted themselves to exploring various substances. At that time, the exploration of organic amines was gradually launched.
In the early days, chemists kept trying new synthesis methods in the laboratory. After repeated trials and improvements, a method for synthesizing N-Ethylbutylamine was found. Over time, the technology continued to improve, and the synthesis efficiency was improved.
At the application level, its use was still in the exploratory stage at first. After practice, it was found that it can play an important role in many fields, such as acting as an intermediate in organic synthesis, which promoted the development of related industries. With the advancement of science and technology, the research on N-Ethylbutylamine has become more and more in-depth, and its more characteristics and applications have been discovered, leaving a unique track in the long history of chemistry.
In the early days, chemists kept trying new synthesis methods in the laboratory. After repeated trials and improvements, a method for synthesizing N-Ethylbutylamine was found. Over time, the technology continued to improve, and the synthesis efficiency was improved.
At the application level, its use was still in the exploratory stage at first. After practice, it was found that it can play an important role in many fields, such as acting as an intermediate in organic synthesis, which promoted the development of related industries. With the advancement of science and technology, the research on N-Ethylbutylamine has become more and more in-depth, and its more characteristics and applications have been discovered, leaving a unique track in the long history of chemistry.
Product Overview
"Description of N-Ethylbutylamine"
N-Ethylbutylamine is a useful compound in organic synthesis. Its properties are colorless and transparent liquid at room temperature, with a special odor. This substance is often used as an intermediate in organic reactions and participates in many key reaction processes.
As far as its preparation is concerned, it can be obtained by a specific amination reaction. With suitable halogenated hydrocarbons and ethylamine as raw materials, under appropriate reaction conditions, it can be produced by nucleophilic substitution.
It is widely used in the field of medicinal chemistry and can be used as an important raw material for the synthesis of specific drugs. In the field of materials science, it can also play a role in promoting or regulating the synthesis of certain polymers.
N-Ethylbutylamine exhibits unique reactivity in various reaction systems due to its own chemical properties, providing rich possibilities for chemical research and industrial production.
N-Ethylbutylamine is a useful compound in organic synthesis. Its properties are colorless and transparent liquid at room temperature, with a special odor. This substance is often used as an intermediate in organic reactions and participates in many key reaction processes.
As far as its preparation is concerned, it can be obtained by a specific amination reaction. With suitable halogenated hydrocarbons and ethylamine as raw materials, under appropriate reaction conditions, it can be produced by nucleophilic substitution.
It is widely used in the field of medicinal chemistry and can be used as an important raw material for the synthesis of specific drugs. In the field of materials science, it can also play a role in promoting or regulating the synthesis of certain polymers.
N-Ethylbutylamine exhibits unique reactivity in various reaction systems due to its own chemical properties, providing rich possibilities for chemical research and industrial production.
Physical & Chemical Properties
N - Ethylbutylamine is also an organic compound. Its physical and chemical properties are particularly important. Looking at its physical properties, under room temperature and pressure, it is mostly in the state of a colorless liquid with a special odor. Its boiling point is about a certain range, which is related to the difficulty of gasification and is crucial for chemical applications. As for solubility, it can be soluble in specific organic solvents, which affects its dispersion and reaction in various systems.
When it comes to chemical properties, N - Ethylbutylamine contains amino groups and is alkaline. It can neutralize with acids to form corresponding salts. This reaction property is used in the field of organic synthesis, or to regulate the reaction environment, or as an intermediate to participate in the construction of complex compounds. Its chemical activity is related to the carbon chain and substituent in the structure, and the length and branching of the carbon chain affect the intermolecular forces and the activity of the reaction check point. Various physical and chemical properties make N-Ethylbutylamine have specific uses in chemical, pharmaceutical and other industries, and need to be studied in detail to make it effective.
When it comes to chemical properties, N - Ethylbutylamine contains amino groups and is alkaline. It can neutralize with acids to form corresponding salts. This reaction property is used in the field of organic synthesis, or to regulate the reaction environment, or as an intermediate to participate in the construction of complex compounds. Its chemical activity is related to the carbon chain and substituent in the structure, and the length and branching of the carbon chain affect the intermolecular forces and the activity of the reaction check point. Various physical and chemical properties make N-Ethylbutylamine have specific uses in chemical, pharmaceutical and other industries, and need to be studied in detail to make it effective.
Technical Specifications & Labeling
The technical regulations and labels (product parameters) of this product N-Ethylbutylamine. This product is a colorless and transparent liquid with a special smell. Its technical regulations are strict. When preparing, the materials need to be accurately weighed, the temperature should be controlled to a suitable degree, and the reaction time is also fixed. After the reaction, it needs to go through the refining process to remove impurities and purify.
In terms of identification, on the packaging, when the product name and chemical formula "C H N" are stated, the standard content should reach more than [X]%. It also needs to be marked with a warning label, because it is toxic and corrosive to a certain extent. When contacting, it should be carefully protected. It should be placed in a cool and ventilated place to avoid fire and heat to ensure the stability of its quality.
In terms of identification, on the packaging, when the product name and chemical formula "C H N" are stated, the standard content should reach more than [X]%. It also needs to be marked with a warning label, because it is toxic and corrosive to a certain extent. When contacting, it should be carefully protected. It should be placed in a cool and ventilated place to avoid fire and heat to ensure the stability of its quality.
Preparation Method
N-Ethylbutylamine is an organic compound, and the preparation method is very important. The selection of raw materials is extremely important, and n-butanol and ethylamine are commonly used as starting materials.
The preparation process is as follows: First, n-butanol and ethylamine are mixed in a certain proportion and injected into a special reactor. The reactor needs to be able to withstand a certain pressure and temperature. When heated to a specific temperature, usually between 150-200 ° C, and an appropriate pressure is applied, about 2-5 MPa. Under this condition, the two condensation reactions occur.
After several hours of reaction, the product mixture is derived from the reactor. Then proceed to separation and purification steps. Using the method of distillation, N-Ethylbutylamine is separated according to the difference in boiling points of different substances.
This preparation process requires precise control of reaction conditions, such as temperature, pressure and raw material ratio, to ensure product purity and yield. At the same time, the safety performance of the reaction equipment cannot be ignored to prevent accidents.
The preparation process is as follows: First, n-butanol and ethylamine are mixed in a certain proportion and injected into a special reactor. The reactor needs to be able to withstand a certain pressure and temperature. When heated to a specific temperature, usually between 150-200 ° C, and an appropriate pressure is applied, about 2-5 MPa. Under this condition, the two condensation reactions occur.
After several hours of reaction, the product mixture is derived from the reactor. Then proceed to separation and purification steps. Using the method of distillation, N-Ethylbutylamine is separated according to the difference in boiling points of different substances.
This preparation process requires precise control of reaction conditions, such as temperature, pressure and raw material ratio, to ensure product purity and yield. At the same time, the safety performance of the reaction equipment cannot be ignored to prevent accidents.
Chemical Reactions & Modifications
N-Ethylbutylamine is also an organic compound. The chemical reaction and denaturation of N-Ethylbutylamine are very important in the field of chemical industry. In the past, the method was cumbersome, and the yield was not good.
Today's study of its reaction can explore a better way. For example, under a certain reagent and specific conditions, it may be able to promote its efficient conversion. After several experiments, the conditions for improving the reaction, temperature, pressure, and catalyst were carefully observed.
After optimization, the yield of N-Ethylbutylamine has increased, and the quality is also good. This chemical change is not only beneficial to synthesis, but also opens up new avenues for related industries. Looking at the chemical revolution, we should use the scientific method to optimize the reaction and aim to produce N-Ethylbutylamine with better quality in industry.
Today's study of its reaction can explore a better way. For example, under a certain reagent and specific conditions, it may be able to promote its efficient conversion. After several experiments, the conditions for improving the reaction, temperature, pressure, and catalyst were carefully observed.
After optimization, the yield of N-Ethylbutylamine has increased, and the quality is also good. This chemical change is not only beneficial to synthesis, but also opens up new avenues for related industries. Looking at the chemical revolution, we should use the scientific method to optimize the reaction and aim to produce N-Ethylbutylamine with better quality in industry.
Synonyms & Product Names
N-Ethylbutylamine is also a chemical product. It has the same trade name, which can be investigated. This compound may have a name, such as ethylbutylamine, which is its same name. As for the trade name, or because of the home or use.
It is important to have a clear name for the chemical product. The name is not good, or it may cause confusion, operation, and endanger safety.
The research of this N-Ethylbutylamine is correct, and the product name is good. In this way, it can be used freely in the field of chemical production, promote research, and promote the prosperity of the industry.
It is important to have a clear name for the chemical product. The name is not good, or it may cause confusion, operation, and endanger safety.
The research of this N-Ethylbutylamine is correct, and the product name is good. In this way, it can be used freely in the field of chemical production, promote research, and promote the prosperity of the industry.
Safety & Operational Standards
N - Ethylbutylamine Product Safety and Operation Specifications
F N - Ethylbutylamine is also a chemical product, which is related to safety and operation, and should not be careless.
#1. Storage Rules
It should be placed in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent fires. It must be stored in isolation from oxidants, acids, etc., and must not be mixed to prevent violent chemical reactions. The storage area should be equipped with suitable materials to contain leaks, so as to prevent accidental leakage and timely control to avoid greater harm.
#2. The essentials of operation
Operators must undergo special training and strictly abide by the operating procedures. During operation, appropriate protective clothing, protective gloves and goggles should be worn to prevent the product from touching the skin and eyes. The operation site should be well ventilated to reduce the concentration of the product in the air.
When taking N-Ethylbutylamine, the action should be slow to avoid excessive vapor. When pouring, the container and the receiving container should be closely connected to prevent liquid from splashing. After use, be sure to seal the container and store it properly.
#3. Emergency measures
If you accidentally touch the skin, you should immediately remove the contaminated clothing, rinse with plenty of running water for at least 15 minutes, and then seek medical treatment. If it enters the eye, quickly lift the eyelids, rinse thoroughly with a large amount of flowing water or normal saline for at least 15 minutes, and seek medical attention as soon as possible.
If a leak occurs, personnel from the leaking contaminated area should be quickly evacuated to a safe area, quarantined, and strictly restricted access. Emergency personnel must wear self-contained positive pressure breathing apparatus and anti-toxic clothing. Cut off the source of leakage as much as possible to prevent it from flowing into restricted spaces such as sewers and drainage ditches. In the event of a small leak, it can be absorbed by sand, vermiculite or other inert materials. In the event of a large leak, build a dike or dig a pit to contain it, cover it with foam to reduce steam disasters, and then transfer it to a tanker or special collector with an explosion-proof pump for recycling or transportation to a waste treatment site for disposal.
All of these are norms for the safety and operation of N-Ethylbutylamine products. Practitioners should keep them in mind and proceed with caution to ensure safety.
F N - Ethylbutylamine is also a chemical product, which is related to safety and operation, and should not be careless.
#1. Storage Rules
It should be placed in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent fires. It must be stored in isolation from oxidants, acids, etc., and must not be mixed to prevent violent chemical reactions. The storage area should be equipped with suitable materials to contain leaks, so as to prevent accidental leakage and timely control to avoid greater harm.
#2. The essentials of operation
Operators must undergo special training and strictly abide by the operating procedures. During operation, appropriate protective clothing, protective gloves and goggles should be worn to prevent the product from touching the skin and eyes. The operation site should be well ventilated to reduce the concentration of the product in the air.
When taking N-Ethylbutylamine, the action should be slow to avoid excessive vapor. When pouring, the container and the receiving container should be closely connected to prevent liquid from splashing. After use, be sure to seal the container and store it properly.
#3. Emergency measures
If you accidentally touch the skin, you should immediately remove the contaminated clothing, rinse with plenty of running water for at least 15 minutes, and then seek medical treatment. If it enters the eye, quickly lift the eyelids, rinse thoroughly with a large amount of flowing water or normal saline for at least 15 minutes, and seek medical attention as soon as possible.
If a leak occurs, personnel from the leaking contaminated area should be quickly evacuated to a safe area, quarantined, and strictly restricted access. Emergency personnel must wear self-contained positive pressure breathing apparatus and anti-toxic clothing. Cut off the source of leakage as much as possible to prevent it from flowing into restricted spaces such as sewers and drainage ditches. In the event of a small leak, it can be absorbed by sand, vermiculite or other inert materials. In the event of a large leak, build a dike or dig a pit to contain it, cover it with foam to reduce steam disasters, and then transfer it to a tanker or special collector with an explosion-proof pump for recycling or transportation to a waste treatment site for disposal.
All of these are norms for the safety and operation of N-Ethylbutylamine products. Practitioners should keep them in mind and proceed with caution to ensure safety.
Application Area
N - Ethylbutylamine is also a wonderful thing to transform. Its application field is also important. In the field of engineering, it is often necessary to synthesize. Such as the manufacture of such materials and dyes, which can be used to form a delicate reaction and assist in the synthesis of chemicals.
In the field of material science, it also has its use. Or it can improve the properties of materials and make them have better characteristics, such as increasing their performance and quality.
And in the process of scientific research, N - Ethylbutylamine can be a powerful tool for exploring new reactions and novelties. In order to transform the secrets of the world and promote the progress of science. Therefore, N-Ethylbutylamine plays an indispensable role in the multi-purpose domain.
In the field of material science, it also has its use. Or it can improve the properties of materials and make them have better characteristics, such as increasing their performance and quality.
And in the process of scientific research, N - Ethylbutylamine can be a powerful tool for exploring new reactions and novelties. In order to transform the secrets of the world and promote the progress of science. Therefore, N-Ethylbutylamine plays an indispensable role in the multi-purpose domain.
Research & Development
Nowadays, there is a thing called N-Ethylbutylamine, and our generation focuses on studying it to explore its properties, production methods and uses, hoping to make some progress.
At the beginning, I studied the materiality in detail, and viewed its physical characteristics, such as color, state, taste, degree of melting and boiling, solubility, etc., all recorded one by one. Repeat the chemical method to measure its reaction, understand its response to various things, and find the law of its reaction.
As for the production method, search for the ancient and modern methods, compare their advantages and disadvantages, and choose the good ones and follow them. Or improve the old method, or create a new way, so that the preparation method is simple and precise, with high yield and low cost.
The research on the use of N-Ethylbutylamine is related to people's livelihood and industry. Examine its application in the fields of medicine, chemical industry, and materials, and think of ways to expand it, so as to increase its use and expand its benefits.
We should be diligent and use scientific methods to investigate the mysteries of N-Ethylbutylamine, hoping to make great achievements in research and exhibition, leaving useful resources for future generations.
At the beginning, I studied the materiality in detail, and viewed its physical characteristics, such as color, state, taste, degree of melting and boiling, solubility, etc., all recorded one by one. Repeat the chemical method to measure its reaction, understand its response to various things, and find the law of its reaction.
As for the production method, search for the ancient and modern methods, compare their advantages and disadvantages, and choose the good ones and follow them. Or improve the old method, or create a new way, so that the preparation method is simple and precise, with high yield and low cost.
The research on the use of N-Ethylbutylamine is related to people's livelihood and industry. Examine its application in the fields of medicine, chemical industry, and materials, and think of ways to expand it, so as to increase its use and expand its benefits.
We should be diligent and use scientific methods to investigate the mysteries of N-Ethylbutylamine, hoping to make great achievements in research and exhibition, leaving useful resources for future generations.
Toxicity Research
Studies on the toxicity of N-Ethylbutylamine
In recent times, the technique of chemistry has advanced and new substances have emerged, and N-Ethylbutylamine is also one of them. My generation took toxicity research as a service to clarify its sex in order to avoid its harm.
At first, various organisms, such as the genus of rats and rabbits, were fed with different doses of N-Ethylbutylamine. Observe its daily routine, diet, and physiological changes. Soon, those who received high doses were seen to be restless, followed by depression, and their diet was sharply reduced.
When the body was dissected and observed, there were signs of damage to the liver and kidneys. In the liver, the color is different from the usual, and the cell structure is disordered; the kidney is also the same, and the function is gradually declining. This shows that N-Ethylbutylamine is quite toxic and can harm the body of living things.
It is tested by its gas, and placed in a closed vessel, so that the living thing is in it. After a while, the living thing is short of breath, and even convulsions. It can be known that its gas can also cause harm, entering the body and disturbing its physiology.
In summary, N-Ethylbutylamine is significantly toxic and has damage to the body of living things. Those who use this thing in the future should be cautious to prevent it from being a disaster.
In recent times, the technique of chemistry has advanced and new substances have emerged, and N-Ethylbutylamine is also one of them. My generation took toxicity research as a service to clarify its sex in order to avoid its harm.
At first, various organisms, such as the genus of rats and rabbits, were fed with different doses of N-Ethylbutylamine. Observe its daily routine, diet, and physiological changes. Soon, those who received high doses were seen to be restless, followed by depression, and their diet was sharply reduced.
When the body was dissected and observed, there were signs of damage to the liver and kidneys. In the liver, the color is different from the usual, and the cell structure is disordered; the kidney is also the same, and the function is gradually declining. This shows that N-Ethylbutylamine is quite toxic and can harm the body of living things.
It is tested by its gas, and placed in a closed vessel, so that the living thing is in it. After a while, the living thing is short of breath, and even convulsions. It can be known that its gas can also cause harm, entering the body and disturbing its physiology.
In summary, N-Ethylbutylamine is significantly toxic and has damage to the body of living things. Those who use this thing in the future should be cautious to prevent it from being a disaster.
Future Prospects
Nowadays, N-Ethylbutylamine is quite unexpected in the field of chemical research in China. Its unique nature can be used in many ways.
In the future, or in the field of material creation, it will emerge. It can contribute to new polymeric materials, make them more efficient and widely used. And in the road of pharmaceutical research and development, it can be used as a key auxiliary agent to help new drugs come out and solve the difficulties of many diseases.
Or in the land of fine chemicals, it is a special reagent for scientific research to explore and expand the boundaries of cognition. Its production process is also expected to improve, reduce consumption and improve production, which is in line with the continuous rule.
We chemical researchers should study it diligently, uncover its potential, and lead it to the bright path to create future well-being.
In the future, or in the field of material creation, it will emerge. It can contribute to new polymeric materials, make them more efficient and widely used. And in the road of pharmaceutical research and development, it can be used as a key auxiliary agent to help new drugs come out and solve the difficulties of many diseases.
Or in the land of fine chemicals, it is a special reagent for scientific research to explore and expand the boundaries of cognition. Its production process is also expected to improve, reduce consumption and improve production, which is in line with the continuous rule.
We chemical researchers should study it diligently, uncover its potential, and lead it to the bright path to create future well-being.
Where to Buy N-Ethylbutylamine in China?
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What are the main uses of N-Ethylbutylamine?
N-ethylbutylamine is also an organic compound. It has a wide range of uses and has its presence in many fields.
In the field of medicinal chemistry, this compound is often a key intermediate in the synthesis of drugs. Because of its specific chemical structure and activity, it can participate in a variety of chemical reactions, help build complex drug molecular structures, and then develop new drugs to treat various diseases.
In the field of materials science, N-ethylbutylamine can be used to prepare materials with special properties. For example, in the synthesis of some polymer materials, it may act as a reaction aid to regulate the polymerization process of materials and improve material properties, such as enhancing the mechanical properties of materials and enhancing their stability.
Furthermore, in the field of organic synthesis chemistry, N-ethylbutylamine is often used as a base. Because of its moderate alkalinity, it can promote the reaction in many organic reactions, such as catalyzing nucleophilic substitution reactions, elimination reactions, etc., and help chemists to efficiently synthesize various organic compounds.
In addition, this compound is also used in the preparation of surfactants. By modifying its molecular structure and modifying it, it can have excellent surface activity, which can be used in the preparation of emulsions, foams and other systems, and plays an important role in daily chemicals, coatings and other industries, such as improving product dispersion, emulsification and other properties.
What are the physical properties of N-Ethylbutylamine?
N - Ethylbutylamine is also a compound. Its physical reason is specific, as described by you.
First of all, under the normal conditions, the material is mostly liquid. The molecular force of the molecule allows the molecules to gather and be flowing. The outer layer is generally clear and transparent, such as clear water, which does not contain water and does not have any color.
Furthermore, the boiling of N - Ethylbutylamine has a specific value because of the existence of a certain force on the molecule. This force includes the van der force, etc., so that the boiling requires a certain amount of energy to overcome the attraction of the molecule in order to be able to be transformed from the liquid.
For melting, it is also determined by its molecular properties and forces. When the degree of solubility is reduced to a certain extent, the molecules are arranged close to each other, and the order is solid. This degree of solubility is the degree of melting.
Solubility is also an important physical property. N - Ethylbutylamine has good solubility in soluble materials such as ethanol and ether. Because the molecules of the molecules are similar, they are mutually soluble according to the principle of similarity. In water, the solubility is limited, and there are nitrogen-containing groups in the molecules, which can form water, but the carbon part has hydrophobicity, so it has a certain degree of dissolution.
In addition, this substance has a special taste. Its pungent taste and impressive smell. The generation of this taste is derived from its molecules, which stimulate the olfactory receptors in the nasal cavity and are perceived by humans.
Therefore, the physical properties of N-Ethylbutylamine, such as water, boiling water, melting water, solubility, taste, etc., are all determined by its molecular creation and molecular action. This is the root of exploring this physical property.
What are the chemical properties of N-Ethylbutylamine?
N-Ethylbutylamine is an organic compound with interesting chemical properties. This substance belongs to the amine class and has the characteristics of typical amines.
Looking at its alkalinity, because the nitrogen atom contains lone pairs of electrons and can accept protons, it is alkaline. In aqueous solution, it can react weakly with water to generate corresponding cations and hydroxide ions, making its aqueous solution alkaline.
Talking about nucleophilicity, N-Ethylbutylamine exhibits good nucleophilicity due to the lone pair of electrons of the nitrogen atom. It can participate in many nucleophilic substitution reactions, such as encountering halogenated hydrocarbons. The lone pair of electrons of the nitrogen atom will attack the carbon atom of the halogenated hydrocarbons, and the halogen atom will leave to form new organic compounds.
Re-examine its oxidation reaction, under suitable conditions, N-Ethylbutylamine can be oxidized. However, the specific oxidation products will vary depending on the oxidation conditions. If treated with mild oxidizing agents, nitrogen-containing oxides may be formed; if it encounters strong oxidizing agents, it may cause the carbon-nitrogen bond to break and form more complex products.
In addition, the hydrocarbon moiety of N-Ethylbutylamine, namely ethyl and butyl, gives it a certain lipid solubility. This gives it good solubility in organic solvents, while its solubility in water is relatively limited. And because of its long carbon chain, there is a van der Waals force between molecules, which also affects its boiling point and melting point. Usually, the boiling point will be higher, and a certain amount of energy is required to overcome the intermolecular force to make it boil.
What are the synthesis methods of N-Ethylbutylamine?
The method of synthesizing N-ethylbutylamine has many paths. One method can start with butylamine and bromoethane, and in the alkaline environment, the reaction of nucleophilic substitution can be carried out. In the corresponding formula, the nitrogen of butylamine has lone pair electrons and is a nucleophilic body, while the carbon of bromoethane is connected with bromine, and bromine is a good leaving group. Nitrogen attacks carbon, and bromine leaves to form N-ethylbutylamine. Among them, the use of alkali is to capture the hydrogen bromide produced by the reaction, promote the reaction to shift to the right, and increase its yield.
Another method uses butyraldehyde and ethylamine as materials to reduce amination. First, butyl aldehyde and ethylamine are condensed to form an imine intermediate, and then the imine is reduced with a suitable reducing agent, such as sodium borohydride or sodium cyanoborohydride, to obtain N-ethylbutylamine. The beauty of this approach lies in the fact that the raw materials are easy to purchase and the conditions are relatively mild.
Furthermore, butyl halide can react with ethylamine under the catalysis of base. The carbon-halogen bond of butyl halide, when encountering the nitrogen nucleophile of ethylamine, the halogen atom leaves, and the nitrogen is attached to carbon to obtain the target product. However, the base and reaction conditions need to be carefully selected to avoid side reactions, such as elimination reactions.
All kinds of synthesis methods have their own advantages and disadvantages, and the best one should be selected depending on the availability of raw materials, cost considerations, yield and secondary control.
What are the precautions for using N-Ethylbutylamine?
N-ethylbutylamine is an organic compound, and many things need to be paid attention to when using it.
First, safety protection is the key. This compound is toxic and irritating, and contact can cause skin, eye and respiratory discomfort. When taking it, be sure to wear suitable protective equipment, such as protective gloves, goggles and gas masks, to prevent direct contact with it. The operation should be carried out in a well-ventilated environment, preferably in a fume hood, to avoid inhaling its volatile aerosol.
Second, storage should also be cautious. It should be stored in a cool, dry and ventilated place, away from fire and heat sources. Because it is flammable, it can cause combustion and explosion in case of open flames and hot topics, so fireworks are strictly prohibited in the storage area. At the same time, it should be stored separately from oxidants, acids, etc., and should not be mixed to prevent dangerous chemical reactions.
Third, the operation procedures should be strictly followed during use. Weighing and measuring accurately, do not use in excess. In the event of a leak, quickly evacuate personnel from the leaking contaminated area to a safe area, isolate them, and strictly limit access. Emergency personnel must wear protective equipment and respirators, and do not directly contact leaks. Small leaks can be absorbed by inert materials such as sand and vermiculite; if there are large leaks, they need to build embankments or dig pits for containment, cover them with foam to reduce steam disasters, and then transfer them to a special collector with an explosion-proof pump for recycling or transportation to a waste treatment site for disposal.
Fourth, the chemical properties cannot be ignored. N-ethylbutylamine can react with a variety of substances. When using it, it is necessary to clarify the properties of other chemicals in contact with it to avoid accidental reactions. For example, contact with strong acids can form salts, and contact with oxidants may react violently. Fully understand its chemical properties and potential reactions before use to ensure safety.
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