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3pentylamine properties applications synthesis
3-Pentylamine related things
1. Properties
3-pentylamine, its molecule has a unique structure. It is a colorless liquid with an ammonia-like stimulating odor. Its boiling point is about 136-138 ° C, which is related to the intermolecular force. Because the molecule contains an amino group and has a certain polarity, the intermolecular force is not weak, so the boiling point is not extremely low. Its density is about 0.779 g/cm ³, which is slightly less than the density of water. And it is soluble in common organic solvents, such as ethanol, ether, etc., and also has a certain solubility in water. This is because the amino group can form hydrogen bonds with water molecules.
II. Application
In the field of organic synthesis, 3-pentylamine has a wide range of uses. It is often used as an important intermediate for the preparation of various nitrogen-containing compounds. For example, the synthesis of drugs with specific structures can participate in many chemical reactions and construct complex drug molecular structures due to the activity of amino groups. In materials science, it is also useful. It can participate in the preparation of some functional polymer materials. By reacting amino groups with other monomers, the materials have specific properties, such as improving the solubility of materials and improving the compatibility of materials with other substances.
III. Synthesis
There are various methods for synthesizing 3-pentylamine. First, it can be prepared by the reaction of 3-pentanol and ammonia under the action of a catalyst. In this process, the hydroxyl group of 3-pentanol is replaced by an amino group. Specifically, under suitable temperature and pressure, active alumina is used as a catalyst to promote the nucleophilic substitution reaction between the two. Another method can be obtained from the reaction of 3-bromopentane with ammonia. The bromine atom of 3-bromopentane is active, and ammonia attacks the bromine atom as a nucleophilic agent, and generates 3-pentamine through a substitution reaction. This reaction is usually carried out in an organic solvent, such as an ethanol solution, to promote the smooth occurrence of the reaction.
1. Properties
3-pentylamine, its molecule has a unique structure. It is a colorless liquid with an ammonia-like stimulating odor. Its boiling point is about 136-138 ° C, which is related to the intermolecular force. Because the molecule contains an amino group and has a certain polarity, the intermolecular force is not weak, so the boiling point is not extremely low. Its density is about 0.779 g/cm ³, which is slightly less than the density of water. And it is soluble in common organic solvents, such as ethanol, ether, etc., and also has a certain solubility in water. This is because the amino group can form hydrogen bonds with water molecules.
II. Application
In the field of organic synthesis, 3-pentylamine has a wide range of uses. It is often used as an important intermediate for the preparation of various nitrogen-containing compounds. For example, the synthesis of drugs with specific structures can participate in many chemical reactions and construct complex drug molecular structures due to the activity of amino groups. In materials science, it is also useful. It can participate in the preparation of some functional polymer materials. By reacting amino groups with other monomers, the materials have specific properties, such as improving the solubility of materials and improving the compatibility of materials with other substances.
III. Synthesis
There are various methods for synthesizing 3-pentylamine. First, it can be prepared by the reaction of 3-pentanol and ammonia under the action of a catalyst. In this process, the hydroxyl group of 3-pentanol is replaced by an amino group. Specifically, under suitable temperature and pressure, active alumina is used as a catalyst to promote the nucleophilic substitution reaction between the two. Another method can be obtained from the reaction of 3-bromopentane with ammonia. The bromine atom of 3-bromopentane is active, and ammonia attacks the bromine atom as a nucleophilic agent, and generates 3-pentamine through a substitution reaction. This reaction is usually carried out in an organic solvent, such as an ethanol solution, to promote the smooth occurrence of the reaction.
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