Shanxian Chemical
SUPPLEMENTS
Allylamine Antifungal Examples
Example of allylamine antifungal drugs
Although fusidic acid is not an allylamine, its antibacterial is unique. Unlike it, allylamine antifungal drugs have a clear mechanism, inhibiting squalene cyclooxygenase, blocking the synthesis of ergosterol, and the damage of fungal cell membranes is difficult to survive.
Among such drugs, terbinafine is well-known. For dermatophytes, whether it is Trichophyton trichomonas causing tinea corporis, tinea corporis, or capitis caused by microsporidia, the curative effect is excellent. And oral absorption is good, wide distribution, and high concentration of drugs on the skin and hair. For example, patients with tinea corporis, taken orally according to the course of treatment, combined with external cream, the symptoms are significantly improved,
Butenafine is also not inferior. It is effective against superficial fungal diseases, especially tinea pedis. Because of its strong lipophilic properties, it can penetrate deep into the stratum corneum of the skin and continue to exert anti-fungal effects. Clinical studies have shown that Butenafine Cream is effective in the treatment of tinea pedis, with few adverse reactions and good patient tolerance.
Naftifen also has a place in the field of antifungal. It is mostly used for local superficial fungal infections, such as tinea pedis. In many external preparations, it can quickly penetrate the skin, inhibit fungal growth, reduce inflammatory reactions, and promote skin damage recovery.
Although fusidic acid is not an allylamine, its antibacterial is unique. Unlike it, allylamine antifungal drugs have a clear mechanism, inhibiting squalene cyclooxygenase, blocking the synthesis of ergosterol, and the damage of fungal cell membranes is difficult to survive.
Among such drugs, terbinafine is well-known. For dermatophytes, whether it is Trichophyton trichomonas causing tinea corporis, tinea corporis, or capitis caused by microsporidia, the curative effect is excellent. And oral absorption is good, wide distribution, and high concentration of drugs on the skin and hair. For example, patients with tinea corporis, taken orally according to the course of treatment, combined with external cream, the symptoms are significantly improved,
Butenafine is also not inferior. It is effective against superficial fungal diseases, especially tinea pedis. Because of its strong lipophilic properties, it can penetrate deep into the stratum corneum of the skin and continue to exert anti-fungal effects. Clinical studies have shown that Butenafine Cream is effective in the treatment of tinea pedis, with few adverse reactions and good patient tolerance.
Naftifen also has a place in the field of antifungal. It is mostly used for local superficial fungal infections, such as tinea pedis. In many external preparations, it can quickly penetrate the skin, inhibit fungal growth, reduce inflammatory reactions, and promote skin damage recovery.
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