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Hydrogen Bonds Importance Exceptions

Exceptions to the importance of hydrogen bonds

The hydrogen bond is related to various biochemical things. However, there are exceptions.

Ordinarily speaking, hydrogen bonds maintain the secondary structure of proteins, so that they follow rules. The peptide chain has an alpha-helical and beta-folded state. If the hydrogen bond is missing, the conformation of the protein will be disordered and the function will be difficult. And in the DNA double helix structure, the pairing of hydrogen bonds between bases ensures the accuracy of genetic information transmission. A is connected to T, G and C by hydrogen bonds, so that the genetic chain is stable. Furthermore, hydrogen bonds between water molecules give water specific physical properties, such as high boiling point and high specific heat, which are key to the temperature balance of life and the transportation of substances.

However, hydrogen bonds are not important. There are interactions between substances, which do not depend on hydrogen bonds. For example, the lattice maintenance of some simple ionic crystals is mainly dominated by ionic bonds, and the electrostatic attractive force between ions is the reason for its structural stability, not the force of hydrogen bonds. For example, in some metal crystals, metal atoms are bonded by metal bonds, and the interaction of electron gas and ionic solid particles builds a stable structure, which is not involved in hydrogen bonds. Another example is that some non-polar small molecules, such as methane, attract each other with a weak van der Waals force, and there is no hydrogen bond involved. From this perspective, although hydrogen bonding is crucial in many biological and chemical phenomena, it is not significant in ionic crystals, metal crystals, and some non-polar small molecule systems. This is an exception to the importance of hydrogen bonding.