Shanxian Chemical
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Hydrogen Peroxide Neuropathy
On hydrogen peroxide and neuropathy
Hydrogen peroxide has profound implications for the physiology and pathology of the human body, and is also a research hotspot.
Hydrogen peroxide is active and has the ability to oxidize. In the microenvironment of nerves, changes in its concentration can lead to a chain reaction. Moderate hydrogen peroxide participates in the conduction of nerve signals and facilitates communication between cells. However, if the concentration is unbalanced and exceeds the body's control, it is a disaster.
When hydrogen peroxide accumulates, its strong oxidation can damage the membrane structure of nerve cells. Membrane is the barrier of cells, the stability of the protection of the inside, and the loss of substances. The membrane is broken, the ion channel is disordered, calcium, sodium and other imbalances, and the transmission of nerve impulses is disturbed, resulting in sensory and motor disorders.
Furthermore, hydrogen peroxide can induce oxidative stress and produce a large number of free radicals. Free radical activity is high, attacking the protein and nucleic acid of nerve cells. Protein damage, the function is wasted; nucleic acid injury, genetic information transmission error. Both of these make nerve cells gradually decline and cause neuropathy.
Looking at all clinical conditions, the patient's symptoms are seen, or the limbs are numb, or the pain is like a thorn, or there is a loss of sensation. The reason is that the harm of hydrogen peroxide may be one of them.
To treat neuropathy, controlling the concentration of hydrogen peroxide is the main way. Modify the body's antioxidant system, increase the effect of glutathione and superoxide dismutase, and resist the harm of hydrogen peroxide. Or develop new drugs, specifically to prevent the production of hydrogen peroxide and slow down the damage of nerves.
In summary, understanding the relationship between hydrogen peroxide and neuropathy points to a clear way to treat this disease. I hope my colleagues in the medical community will deeply study their principles and find better ways to solve the suffering of patients.
Hydrogen peroxide has profound implications for the physiology and pathology of the human body, and is also a research hotspot.
Hydrogen peroxide is active and has the ability to oxidize. In the microenvironment of nerves, changes in its concentration can lead to a chain reaction. Moderate hydrogen peroxide participates in the conduction of nerve signals and facilitates communication between cells. However, if the concentration is unbalanced and exceeds the body's control, it is a disaster.
When hydrogen peroxide accumulates, its strong oxidation can damage the membrane structure of nerve cells. Membrane is the barrier of cells, the stability of the protection of the inside, and the loss of substances. The membrane is broken, the ion channel is disordered, calcium, sodium and other imbalances, and the transmission of nerve impulses is disturbed, resulting in sensory and motor disorders.
Furthermore, hydrogen peroxide can induce oxidative stress and produce a large number of free radicals. Free radical activity is high, attacking the protein and nucleic acid of nerve cells. Protein damage, the function is wasted; nucleic acid injury, genetic information transmission error. Both of these make nerve cells gradually decline and cause neuropathy.
Looking at all clinical conditions, the patient's symptoms are seen, or the limbs are numb, or the pain is like a thorn, or there is a loss of sensation. The reason is that the harm of hydrogen peroxide may be one of them.
To treat neuropathy, controlling the concentration of hydrogen peroxide is the main way. Modify the body's antioxidant system, increase the effect of glutathione and superoxide dismutase, and resist the harm of hydrogen peroxide. Or develop new drugs, specifically to prevent the production of hydrogen peroxide and slow down the damage of nerves.
In summary, understanding the relationship between hydrogen peroxide and neuropathy points to a clear way to treat this disease. I hope my colleagues in the medical community will deeply study their principles and find better ways to solve the suffering of patients.
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